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Comas

Part of Omnia Technologies Life Sciences
overview

Comas designs and manufactures advanced liquid filling technologies for the pharmaceutical, cosmetic and diagnostic industries.

Comas has been part of Omnia Technologies since 2023.

The company delivers customized machines and integrated lines engineered to ensure high dosing accuracy, reliable performance and full compliance with GMP and FDA standards. Solutions are tailored to meet specific product characteristics, container types and production requirements.

The portfolio includes a wide range of technologies for liquid filling, stoppering and capping, designed to operate in both sterile and non-sterile environments. Particular attention is given to flexibility, process reliability and ease of validation, supporting manufacturers in meeting the most stringent regulatory standards.

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Comas

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About us

Our History

Founded in 1979 in San Casciano Val di Pesa, near Florence, Comas specializes in the design and manufacturing of machines for liquid filling and container capping.
Over the years the company has expanded its technological portfolio by developing solutions for the packaging industry, while maintaining filling technology as its core business. Today Comas operates internationally with more than 1,200 machines installed in over 40 countries and supports customers throughout every stage of the project, from design to training and technical assistance.
Thanks to strong engineering expertise and a continuous focus on innovation, the company develops advanced technologies for packaging processes in the pharmaceutical and cosmetic industries.
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Our Technologies

Backed by over 40 years of experience in liquid processing, Comas designs and manufactures systems for filling and capping, specifically developed for pharmaceutical and medical applications.

Thanks to extensive know-how and years of experience, Comas achieves very high production capacity (over 200 pieces/minute) while maintaining top accuracy and quality in compliance with GMP, FDA, and CE guidelines.

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A global network, close to you

With 25 sales and service offices, technical hubs and partners worldwide, Omnia Technologies combines the strength of a global presence with prompt local support.

Wherever the customer is located, they can rely on responsive assistance, locally available spare parts and qualified technicians who speak their language, ensuring smoother operations and faster interventions.

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Our sustainability journey

Sustainability is at the heart of all Omnia Technologies’ activities. The company is proud to be B Corp certified, rated Silver by Ecovadis and compliant with international standards of the Integrated Management System (ISO).

These certifications represent a concrete commitment to environmental responsibility, ethical governance and transparency, making Omnia Technologies a reliable and conscientious partner.

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Our experts at your disposal

Do you need assistance?

Our service team is ready to provide support and assist you in managing your system.

Comas products

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  • Comas
    Bottles
    Up to 18.000 pcs/h

    RFC (8 or 12 heads)

    RFC is a continuous-motion filling and capping monoblock designed for high-performance liquid production in plastic bottles and vials. Available with 8 or 12 filling syringes according to required output and process configuration, the platform combines precise liquid dosing, synchronized container handling and reliable closure application within a compact and efficient machine architecture. Developed for pharmaceutical and nutraceutical manufacturing environments, RFC integrates continuous-motion bottle transport, configurable filling systems and flexible capping solutions to support stable production conditions and repeatable process performance across different container formats. Engineered for operational reliability and production efficiency, the machine features fast format changeovers, simplified cleaning procedures and intuitive machine accessibility, ensuring smooth integration into complete packaging lines and consistent daily production performance.
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  • Comas
    Vials
    Up to 1.800 pcs/h

    Piccola Powder

    A compact standalone machine designed for small-batch aseptic powder filling of injectable vials in pharmaceutical and biotechnological manufacturing environments. The machine supports flexible production requirements for development, clinical and pilot-scale manufacturing while ensuring controlled and repeatable dosing performance. Its compact architecture, intuitive operation and accessible design allow fast setup, simplified cleaning procedures and efficient integration into sterile and controlled production areas. Designed for operational flexibility and reliable small-scale processing, PICCOLA POWDER is an ideal solution for pharmaceutical powder filling applications requiring precision, repeatability and reduced production footprint.
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  • Comas
    Diagnostic IVD
    Up to 18.000 pcs/h

    Micro Testube Fill

    MICRO TEST TUBE FILL is an automatic filling and capping machine designed for diagnostic microtube production in laboratory and IVD applications. The platform supports accurate reagent dosing, controlled microtube handling and reliable closure application, ensuring repeatable production performance and product integrity. Compact architecture, automated process management and flexible machine configuration make the system suitable for modern diagnostic manufacturing environments requiring precision, scalability and operational efficiency.
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  • Comas
    Vials
    Ophthalmic
    Up to 18,000 pcs/h

    Omnifill

    OMNIFILL is a compact and versatile filling and capping platform designed to combine high production efficiency with reduced machine footprint through its advanced combined-motion architecture. Designed for pharmaceutical manufacturing environments, OMNIFILL supports a wide range of container formats and aseptic filling applications, including sterile ophthalmic packaging processe Engineered for pharmaceutical production, Omnifill is suitable for ophthalmic packaging, ensuring controlled aseptic processing, high accessibility and efficient operation within a compact layout.
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  • Comas
    Diagnostic IVD
    Up to 10.800 pcs/h

    Closed Testube Fill

    CLOSED TEST TUBE FILL is a continuous-motion filling and closing platform designed for closed diagnostic test tube production processes. Developed for high-throughput IVD manufacturing environments, the system supports automated filling, closure and handling operations for diagnostic transport media and sample collection applications. Continuous-motion architecture, synchronized tube handling and reliable closure operations ensure stable production performance, product protection and process repeatability across demanding diagnostic workflows.
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  • Comas
    Diagnostic IVD
    Up to 14.400 pcs/h

    Testube Fill

    TEST TUBE FILL is an automatic filling and capping platform designed for diagnostic test tubes used in IVD and laboratory applications. Engineered for accurate reagent filling and reliable closure application, the system supports controlled and repeatable production processes across different tube formats and liquid formulations. Compact machine layout, automated handling and intuitive operation ensure efficient integration into diagnostic production environments while supporting process reliability and operational flexibility.
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  • Comas
    Strips
    Up to 2,400 pcs/h

    Stripfill

    Compact automatic filling and sealing machine designed for single-dose strip vials. Its innovative U-shaped layout significantly reduces the machine footprint while ensuring a smooth and continuous production flow. The system seals each vial immediately after filling, enhancing product protection, unit integrity and process reliability. Configurable filling systems and controlled heat-sealing technologies ensure precision, consistency and repeatable results, even in demanding pharmaceutical applications. Highly automated, efficient and user-friendly, STRIPFILL is an ideal solution for pharmaceutical and healthcare single-dose packaging applications where compact design, product protection and operational reliability are essential.
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  • Comas
    Cartridges
    Up to 12.000 pcs/h

    Carpulfill

    CARPULFILL is a continuous-motion filling and capping machine designed for dental carpules and injectable cartridges in pharmaceutical and biotechnological manufacturing environments. Engineered for high production efficiency and dosing accuracy, the machine combines continuous handling with synchronized filling and closing operations. Cartridges are precisely tracked throughout the process, ensuring stable positioning, consistent dosing and reliable closure quality even at high production speeds. The platform integrates automatic cartridge loading, stopper insertion, filling and crimping within a compact and robust architecture. Multiple control systems verify cartridge presence, stopper positioning and cap application, guaranteeing process integrity and product safety at every stage. Accurate, scalable and engineered for demanding sterile workflows, CARPULFILL supports high-performance cartridge and dental carpule filling operations with reliable process control and repeatable production quality.
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  • Comas
    Vials
    Up to 1.800 pcs/h

    Piccola Liquid

    A compact standalone machine designed for small-batch processing of injectable vials, ophthalmic products and sterile liquid or powder applications. Engineered for pharmaceutical and biotechnological environments, it supports flexible production needs while ensuring controlled and repeatable processing. Thanks to its compact design and intuitive operation, the machine is ideal for clinical and pilot‑scale manufacturing, allowing fast setup, easy handling and efficient cleaning procedures.
    Contacto
  • Comas
    Bottles
    Up to 15.000 pcs/h

    Orafill

    A continuous-motion automatic filling and capping platform designed for plastic bottles and vials, including round, square and shaped container formats. Engineered for high-throughput production and reliable operation, ORALFILL combines precise liquid dosing with synchronized container handling and controlled closure application within a compact and efficient machine architecture. Built with durable pharmaceutical-grade materials and an intuitive machine layout, ORALFILL integrates automatic container feeding, configurable filling systems and flexible capping solutions, adapting to a wide range of products, formats and production requirements. Its continuous-motion transport architecture ensures smooth handling even with complex container geometries, supporting process stability, dosing accuracy and repeatable production performance across different operating conditions. Designed for operational efficiency and simplified maintenance, ORALFILL features fast format changeovers, easy cleaning access and reliable integration into complete pharmaceutical and nutraceutical packaging lines.
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  • Comas
    Vials
    Ophthalmic
    Up to 7.200 pcs/h

    FD120

    FD120 is a compact automatic aseptic filling and closing machine designed for injectable and ophthalmic vials in pharmaceutical and biotechnological manufacturing environments. Engineered to operate under aseptic conditions, FD120 ensures precise liquid dosing and controlled closure application within a highly accessible and robust platform. The machine is optimized for integration with laminar airflow systems and sterile processing requirements, guaranteeing product integrity and contamination control. Fast format changeover, intuitive operation and efficient cleaning procedures make FD120SI a reliable solution for sterile liquid filling processes where regulatory compliance, repeatability and process safety are critical.
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